DOK ROK Pharmaceuticals & Healthcare

“Whether mushroom supplements, when properly developed and used, have the potential to positively influence the health and well-being of society. And whether it is possible to use mushroom supplements responsibly and effectively to achieve demonstrable health benefits?”

Mushroom supplements, when carefully applied and considering these aspects, can make a positive contribution to health. An individual approach and guidance from professionals are crucial to ensuring that they align with the needs and goals of each individual and are used safely. There is a clear genomic similarity between humans and multicellular fungi, which in some cases, such as simultaneous intake of supplements and systemic antibiotic or antifungal therapy, may be contraindicated.

What do genomic similarities between humans and multicellular fungi mean?

Genetic research on organisms has made significant progress in recent years, allowing us to better understand the similarities and differences between various species. Although humans and multicellular fungi such as Chaga mushrooms, Reishi mushrooms, the Lion’s Mane mushroom (Hericium), and Cordyceps species are fundamentally different in terms of their biological classification, there are remarkable overlaps at the genetic level:

1. Eukaryotic Cell Structure: Humans and multicellular fungi are eukaryotic organisms, meaning their cells have a well-defined cell membrane, a cell nucleus, and organelles such as mitochondria (including the production of adenosine triphosphate (ATP) in large quantities during cell respiration. This involves glycolysis, the citric acid cycle, and the respiratory chain), Golgi apparatus, and endoplasmic reticulum. This commonality in cell structure is a fundamental characteristic of eukaryotes.
2. DNA Structure: The basic structure of DNA (deoxyribonucleic acid) is similar in humans and multicellular fungi. The DNA of both groups consists of a double helix composed of four nucleotides: adenine (A), thymine (T), cytosine (C), and guanine (G). These nucleotides form the genetic code language in which genetic information is encoded.
3. Genetic Code: Humans and multicellular fungi use the same genetic code to translate DNA sequences into proteins. This universal genetic code is crucial for the synthesis of proteins that perform vital functions in both groups.
4. Gene Regulation: Both groups have mechanisms for regulating gene activity. Gene regulation allows organisms to adjust their gene expression to environmental conditions and produce or suppress specific proteins as needed.
5. Metabolic Pathways: There are similarities in basic metabolic pathways between humans and multicellular fungi. This particularly concerns metabolic processes such as energy metabolism, the synthesis of important molecules, and the breakdown of nutrients.

Despite these genetic similarities, it is important to emphasize that humans and fungi are fundamentally different organisms due to their biological distinctions. Humans belong to the animal kingdom (Animalia), while multicellular fungi belong to the fungus kingdom (Fungi). These differences lead to significant divergences in their biology, life cycles, and physiological characteristics. Research into genomic similarities provides insights into the evolutionary history of life on Earth and supports biomedical research by indicating potential applications of fungi and their genes in medicine, dietary supplements, and as alternative antibiotics.

Your Dok Rok Team